symbiont-mediated perturbation of host cell cycle G0/G1 transition checkpoint

Term ID

GO:0039646

Synonyms

• G0/G1 host cell cycle checkpoint dysregulation by virus
• modulation by virus of host G0/G1 transition checkpoint
• perturbation by virus of host G0/G1 transition checkpoint

Definition

A process in which a symbiont interferes with the normal execution of the host cell G0/G1 transition checkpoint. The host is defined as the larger of the organisms involved in a symbiotic interaction. Some viruses benefit from keeping cells in resting state (G0), while others favor entry through G1 and subsequent cell division to replicate more efficiently.

References

• VZ:881

Ontology

GO: Biological Process    QuickGO    AmiGO