Search Ontology:
GO: Biological Process

RIG-I signaling pathway

Term ID
GO:0039529
Synonyms
  • DDX58 signaling pathway
  • retinoic acid inducible gene I signaling pathway
  • RIG-I signalling pathway
  • RIG-I-like receptor (RLR) signaling pathway
  • RIG-like helicase signaling pathway
  • RIG-like receptor signaling pathway
  • RLH signaling pathway
  • RLR signaling pathway
Definition
The series of molecular signals initiated by the binding ssRNA or dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58). RIG-I detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines. (4)
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is a type of
negatively regulated by
positively regulated by
regulated by
Phenotype
Phenotype caused by Genes