Search Ontology:
GO: Biological Process
RIG-I signaling pathway
- Term ID
- GO:0039529
- Synonyms
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- DDX58 signaling pathway
- retinoic acid inducible gene I signaling pathway
- RIG-I signalling pathway
- RIG-I-like receptor (RLR) signaling pathway
- RIG-like helicase signaling pathway
- RIG-like receptor signaling pathway
- RLH signaling pathway
- RLR signaling pathway
- Definition
- The series of molecular signals initiated by the binding ssRNA or dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58). RIG-I detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines. (4)
- References
- Ontology
- GO: Biological Process QuickGO AmiGO
- is a type of
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- negatively regulated by
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- positively regulated by
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- regulated by
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Phenotype
Phenotype caused by Genes