Search Ontology:
GO: Biological Process

ERBB2-EGFR signaling pathway

Term ID
GO:0038134
Synonyms
  • EGFR-HER2 signaling pathway
  • ERBB2-EGFR signalling pathway
Definition
The series of molecular signals initiated by binding of a ligand to an epidermal growth factor receptor (EGFR/ERBB1) on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and EGFR. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR. 16460914
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes