Search Ontology:
GO: Biological Process

ERBB2-ERBB3 signaling pathway

Term ID
GO:0038133
Synonyms
  • ERBB2-ERBB3 signalling pathway
  • HER2-HER3 signaling pathway
Definition
The series of molecular signals initiated by binding of a ligand to a ERBB3 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB3. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB3. ERBB3 also has impaired kinase activity and relies on ERBB2 for activation and signal transmission. 16460914
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes