TRIF-dependent toll-like receptor 4 signaling pathway

Term ID

GO:0035667

Synonyms

• Toll/IL-1 receptor (TIR) domain-containing adaptor-dependent TLR4 signaling pathway
• TRIF-dependent TLR4 signaling pathway
• TRIF-dependent toll-like receptor 4 signalling pathway

Definition

The series of molecular signals initiated by a ligand binding to a toll-like 4 receptor where the TRIF adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response. (2)

References

Ontology

GO: Biological Process    QuickGO    AmiGO