tumor necrosis factor production

Term ID

GO:0032640

Synonyms

• cachectin production
• TNF alpha biosynthesis
• TNF biosynthesis
• TNF biosynthetic process
• TNF production
• TNF-alpha biosynthesis
• TNF-alpha biosynthetic process
• TNF-alpha production
• Tnfa production
• tumor necrosis factor anabolism
• tumor necrosis factor biosynthesis
• tumor necrosis factor biosynthetic process
• tumor necrosis factor formation
• tumor necrosis factor secretion
• tumor necrosis factor synthesis
• tumor necrosis factor-alpha production

Definition

The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Tumor necrosis factor is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis. (2)

References

Ontology

GO: Biological Process    QuickGO    AmiGO