protein kinase A signaling

Term ID

GO:0010737

Synonyms

• PKA signaling cascade
• protein kinase A signal transduction
• protein kinase A signaling cascade
• protein kinase A signalling cascade

Definition

An intracellular signaling cassette that starts with the activation of protein kinase A (PKA), and ends with the regulation of a downstream cellular process, e.g. transcription. The PKA catalytic subunit (PKA-C) is normally present in a complex with its regulatory subunit, PKA-R. The inhibitory action of PKA-R is released upon cAMP binding, which results in the activation of PKA-C. (2)

References

Ontology

GO: Biological Process    QuickGO    AmiGO