granzyme-mediated apoptotic signaling pathway

Term ID

GO:0008626

Synonyms

• apoptotic signaling pathway in response to granzyme
• induction of apoptosis by granzyme

Definition

The series of molecular signals induced by granzymes which triggers the apoptotic death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of apoptosis is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce apoptosis in target cells. 17158907

References

Ontology

GO: Biological Process    QuickGO    AmiGO