ceramide glucosyltransferase activity

Term ID

GO:0008120

Synonyms

• ceramide:UDP-glucose glucosyltransferase activity
• ceramide:UDPGlc glucosyltransferase activity
• glucosylceramide synthase activity
• UDP-glucose-ceramide glucosyltransferase activity
• UDP-glucose:ceramide glucosyltransferase activity
• UDP-glucose:N-acylsphingosine D-glucosyltransferase activity
• UDPglucose:N-acylsphingosine D-glucosyltransferase activity
• uridine diphosphoglucose-ceramide glucosyltransferase activity

Definition

Catalysis of the reaction: an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H+ + UDP.

References

• EC:2.4.1.80
• MetaCyc:CERAMIDE-GLUCOSYLTRANSFERASE-RXN
• RHEA:12088
• Reactome:R-HSA-1638104

Ontology

GO: Molecular Function    QuickGO    AmiGO