thiopurine S-methyltransferase activity

Term ID

GO:0008119

Synonyms

• 6-thiopurine transmethylase activity
• mercaptopurine methyltransferase activity
• S-adenosyl-L-methionine:thiopurine S-methyltransferase activity
• thiopurine methyltransferase activity
• TPMT

Definition

Catalysis of the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether. 2.1.1.67

References

• EC:2.1.1.67
• MetaCyc:THIOPURINE-S-METHYLTRANSFERASE-RXN
• Reactome:R-HSA-158609
• Reactome:R-HSA-5603379
• Reactome:R-HSA-9748979
• Reactome:R-HSA-9748983

Ontology

GO: Molecular Function    QuickGO    AmiGO