DNA repair

Term ID

GO:0006281

Synonyms

Definition

The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. 11563486

References

Wikipedia:DNA_repair

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

has parts: DNA ligation involved in DNA repair DNA synthesis involved in DNA repair

DNA ligation involved in DNA repair DNA synthesis involved in DNA repair Show first 5 Terms
is a type of: DNA damage response DNA metabolic process

DNA damage response DNA metabolic process Show first 5 Terms
has subtype: base-excision repair chromosomal 5-methylcytosine DNA demethylation, oxidative deamination pathway DNA alkylation repair DNA replication proofreading double-strand break repair ... Show All 17 Terms

base-excision repair chromosomal 5-methylcytosine DNA demethylation, oxidative deamination pathway DNA alkylation repair DNA replication proofreading double-strand break repair interstrand cross-link repair mismatch repair mitochondrial DNA repair non-photoreactive DNA repair nucleotide-excision repair postreplication repair protein-DNA covalent cross-linking repair pyrimidine dimer repair recombinational repair single strand break repair UV-damage excision repair viral DNA repair Show first 5 Terms
negatively regulated by: negative regulation of DNA repair

negative regulation of DNA repair Show first 5 Terms
positively regulated by: positive regulation of DNA repair

positive regulation of DNA repair Show first 5 Terms
regulated by: regulation of DNA repair

regulation of DNA repair Show first 5 Terms

Phenotype

Phenotype caused by Genes