TIM23 mitochondrial import inner membrane translocase complex

Term ID

GO:0005744

Synonyms

• mitochondrial inner membrane pre-sequence translocase complex
• mitochondrial inner membrane presequence translocase complex
• mitochondrial inner membrane translocase complex
• Tim23 complex

Definition

The protein transport machinery of the mitochondrial inner membrane that typically transports proteins that possess a matrix-targeting N-terminal presequence. The TIM23 complex contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor. (2)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO