thyroxine 5'-deiodinase activity

Term ID

GO:0004800

Synonyms

• acceptor:3,5,3'-triiodo-L-thyronine oxidoreductase (iodinating)
• diiodothyronine 5'-deiodinase activity
• iodothyronine 5'-deiodinase activity
• iodothyronine outer ring monodeiodinase activity
• L-thyroxine iodohydrolase (reducing) activity
• outer ring-deiodinating pathway
• thyroxine 5' deiodinase activity
• thyroxine deiodinase activity
• type I iodothyronine deiodinase activity
• type II iodothyronine deiodinase activity

Definition

Catalysis of the reaction: 3,5,3'-L-triiodo-L-thyronine + iodide + acceptor + H+ = L-thyroxine + donor-H2. 1.21.99.4

References

• EC:1.21.99.4
• MetaCyc:THYROXINE-DEIODINASE-RXN
• RHEA:19745
• Reactome:R-HSA-209772
• Reactome:R-HSA-350869

Ontology

GO: Molecular Function    QuickGO    AmiGO