all-trans-retinol dehydrogenase (NAD+) activity

Term ID

GO:0004745

Synonyms

• all-trans retinol dehydrogenase activity
• retinal reductase activity
• retinene reductase activity
• retinol (vitamin A1) dehydrogenase activity
• retinol dehydrogenase activity

Definition

Catalysis of the reaction: all-trans-retinol--[retinol-binding protein] + NAD+ = all-trans-retinal--[retinol-binding protein] + H+ + NADH. Recognizes the substrate both in free form and when bound to cellular-retinol-binding-protein (CRBP1), but has higher affinity for the bound form.

References

• EC:1.1.1.105
• MetaCyc:RETINOL-DEHYDROGENASE-RXN
• RHEA:48488
• Reactome:R-HSA-2454081
• Reactome:R-HSA-2466832
• Reactome:R-HSA-5362518
• Reactome:R-HSA-5362564
• Reactome:R-HSA-5362721

Ontology

GO: Molecular Function    QuickGO    AmiGO