Search Ontology:
GO: Molecular Function
phospholipase A2 activity
- Term ID
- GO:0004623
- Synonyms
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- cytosolic phospholipase A2 activity
- lecithinase A activity
- phosphatidase activity
- phosphatidolipase activity
- phosphatidylcholine 2-acylhydrolase activity
- phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
- phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
- secreted phospholipase A2 activity
- Definition
- Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospholipid + H2O = 1-acyl-sn-glycero-3-phospholipid + a fatty acid. This reaction removes the fatty acid attached to the sn2-position. Substrates include phosphatidylcholine, phosphatidylethanolamine, choline plasmalogen and phosphatides.
- References
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- EC:3.1.1.4
- MetaCyc:PHOSPHOLIPASE-A2-RXN
- MetaCyc:RXN-15067
- RHEA:15801
- Reactome:R-HSA-1482604
- Reactome:R-HSA-1482656
- Reactome:R-HSA-1482679
- Reactome:R-HSA-1482745
- Reactome:R-HSA-1482759
- Reactome:R-HSA-1482771
- Reactome:R-HSA-1482776
- Reactome:R-HSA-1482778
- Reactome:R-HSA-1482816
- Reactome:R-HSA-1482825
- Reactome:R-HSA-1482856
- Reactome:R-HSA-1482868
- Reactome:R-HSA-1482884
- Reactome:R-HSA-1482887
- Reactome:R-HSA-1482897
- Reactome:R-HSA-1482900
- Reactome:R-HSA-1482907
- Reactome:R-HSA-1602368
- Reactome:R-HSA-1602374
- Reactome:R-HSA-1602377
- Reactome:R-HSA-1602398
- Reactome:R-HSA-1602399
- Reactome:R-HSA-1602417
- Reactome:R-HSA-1602446
- Reactome:R-HSA-8848484
- Ontology
- GO: Molecular Function QuickGO AmiGO
- is a type of
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- has subtype
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- negatively regulated by
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- positively regulated by
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- regulated by
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Phenotype
Phenotype caused by Genes