phosphatidylinositol phospholipase C activity

Term ID

GO:0004435

Synonyms

• 1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity
• 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity
• 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase activity
• monophosphatidylinositol phosphodiesterase activity
• phosphatidylinositol-4,5-bisphosphate hydrolysis
• phosphoinositidase C activity
• phosphoinositide phospholipase C activity
• PI-PLC activity
• triphosphoinositide phosphodiesterase activity

Definition

Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H+. 3.1.4.11

References

• EC:3.1.4.11
• KEGG_REACTION:R03435
• MetaCyc:3.1.4.11-RXN
• RHEA:33179
• Reactome:R-HSA-111879
• Reactome:R-HSA-167686
• Reactome:R-HSA-1855177
• Reactome:R-HSA-1855214
• Reactome:R-HSA-1855221
• Reactome:R-HSA-202407
• Reactome:R-HSA-2730847
• Reactome:R-HSA-5607735
• Reactome:R-HSA-622382
• Reactome:R-HSA-9032478
• Reactome:R-HSA-9717205

Ontology

GO: Molecular Function    QuickGO    AmiGO