Search Ontology:
GO: Molecular Function

cysteine-type endopeptidase activity

Term ID
GO:0004197
Synonyms
  • lysosomal cysteine-type endopeptidase
  • metacaspase activity
  • thiol endopeptidase activity
Definition
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. (2)
References
  • EC:3.4.22.-
  • Reactome:R-HSA-114252
  • Reactome:R-HSA-114259
  • Reactome:R-HSA-114261
  • Reactome:R-HSA-1236948
  • Reactome:R-HSA-139898
  • Reactome:R-HSA-139952
  • Reactome:R-HSA-1678920
  • Reactome:R-HSA-1678981
  • Reactome:R-HSA-201595
  • Reactome:R-HSA-201603
  • Reactome:R-HSA-201608
  • Reactome:R-HSA-201611
  • Reactome:R-HSA-201622
  • Reactome:R-HSA-201628
  • Reactome:R-HSA-201629
  • Reactome:R-HSA-201630
  • Reactome:R-HSA-201631
  • Reactome:R-HSA-201634
  • Reactome:R-HSA-201636
  • Reactome:R-HSA-201637
  • Reactome:R-HSA-201639
  • Reactome:R-HSA-201640
  • Reactome:R-HSA-2028692
  • Reactome:R-HSA-2028697
  • Reactome:R-HSA-202917
  • Reactome:R-HSA-202939
  • Reactome:R-HSA-202947
  • Reactome:R-HSA-202960
  • Reactome:R-HSA-202966
  • Reactome:R-HSA-202967
  • Reactome:R-HSA-202969
  • Reactome:R-HSA-211186
  • Reactome:R-HSA-211190
  • Reactome:R-HSA-211651
  • Reactome:R-HSA-212552
  • Reactome:R-HSA-2130336
  • Reactome:R-HSA-2130349
  • Reactome:R-HSA-2130504
  • Reactome:R-HSA-2130706
  • Reactome:R-HSA-2562564
  • Reactome:R-HSA-264865
  • Reactome:R-HSA-264871
  • Reactome:R-HSA-3465448
  • Reactome:R-HSA-350158
  • Reactome:R-HSA-350318
  • Reactome:R-HSA-350319
  • Reactome:R-HSA-350651
  • Reactome:R-HSA-351849
  • Reactome:R-HSA-351871
  • Reactome:R-HSA-351876
  • Reactome:R-HSA-351877
  • Reactome:R-HSA-351894
  • Reactome:R-HSA-351901
  • Reactome:R-HSA-351913
  • Reactome:R-HSA-351936
  • Reactome:R-HSA-352268
  • Reactome:R-HSA-418845
  • Reactome:R-HSA-418846
  • Reactome:R-HSA-418852
  • Reactome:R-HSA-448703
  • Reactome:R-HSA-5357828
  • Reactome:R-HSA-5634228
  • Reactome:R-HSA-5660663
  • Reactome:R-HSA-5681987
  • Reactome:R-HSA-5682377
  • Reactome:R-HSA-6800797
  • Reactome:R-HSA-6814387
  • Reactome:R-HSA-9012556
  • Reactome:R-HSA-9013895
  • Reactome:R-HSA-933532
  • Reactome:R-HSA-9603534
  • Reactome:R-HSA-9647632
  • Reactome:R-HSA-9647680
  • Reactome:R-HSA-9647999
  • Reactome:R-HSA-9684273
  • Reactome:R-HSA-9684309
  • Reactome:R-HSA-9684321
  • Reactome:R-HSA-9684336
  • Reactome:R-HSA-9684340
  • Reactome:R-HSA-9684351
  • Reactome:R-HSA-9684352
  • Reactome:R-HSA-9686088
  • Reactome:R-HSA-9686930
  • Reactome:R-HSA-9693929
  • Reactome:R-HSA-9694338
  • Reactome:R-HSA-9694377
  • Reactome:R-HSA-9694441
  • Reactome:R-HSA-9694551
  • Reactome:R-HSA-9694601
  • Reactome:R-HSA-9694625
  • Reactome:R-HSA-9694732
  • Reactome:R-HSA-9697750
  • Reactome:R-HSA-9710101
  • Reactome:R-HSA-9729704
  • Reactome:R-HSA-9729730
  • Reactome:R-HSA-9729741
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
has subtype
negatively regulated by
positively regulated by
Phenotype
Phenotype caused by Genes