Search Ontology:
GO: Molecular Function

DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity

Term ID
GO:0003918
Synonyms
  • deoxyribonucleate topoisomerase
  • deoxyribonucleic topoisomerase activity
  • DNA gyrase activity
  • DNA topoisomerase (ATP-hydrolysing)
  • DNA topoisomerase II
  • DNA topoisomerase II activity
  • DNA topoisomerase IV activity
  • DNA topoisomerase type II activity
  • DNA-gyrase activity
  • topoisomerase
  • topoisomerase II
  • type II DNA topoisomerase activity
Definition
Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2. 8811192
References
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
has subtype
negatively regulated by
positively regulated by
regulated by
Phenotype
Phenotype caused by Genes
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