Search Ontology:
GO: Molecular Function
DNA-(apurinic or apyrimidinic site) endonuclease activity
- Term ID
- GO:0003906
- Synonyms
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- AP endonuclease class I activity
- AP site-DNA 5'-phosphomonoester-lyase activity
- apurinic/apyrimidinic endodeoxyribonuclease activity
- deoxyribonuclease (apurinic or apyrimidinic) activity
- DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase activity
- endonuclease VIII activity
- UV endonuclease
- Definition
- Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER). AP_endonuclease
- References
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- Reactome:R-HSA-110375
- Reactome:R-HSA-5649711
- Reactome:R-HSA-5649725
- Ontology
- GO: Molecular Function QuickGO AmiGO
- is a type of
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- has subtype
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Phenotype
Phenotype caused by Genes