beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity

Term ID

GO:0003829

Synonyms

• beta(6)-N-acetylglucosaminyltransferase activity
• beta6-N-acetylglucosaminyltransferase activity
• core 2 acetylglucosaminyltransferase activity
• core 6-beta-GlcNAc-transferase A
• O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I activity
• UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R) beta-1,6-N-acetyl-D-glucosaminyltransferase activity
• uridine diphosphoacetylglucosamine-mucin beta-(1,6)-acetylglucosaminyltransferase activity
• uridine diphosphoacetylglucosamine-mucin beta-(1->6)-acetylglucosaminyltransferase activity

Definition

Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R = UDP + beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-D-galactosaminyl-R. This reaction is the addition of N-acetyl-alpha-D-glucosamine to the core 1 structure of O-glycans forming core 2. 2.4.1.102

References

• EC:2.4.1.102
• MetaCyc:2.4.1.102-RXN
• RHEA:18705
• Reactome:R-HSA-914012
• Reactome:R-HSA-914018

Ontology

GO: Molecular Function    QuickGO    AmiGO