nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

Term ID

GO:0000288

Synonyms

deadenylation-dependent mRNA decay
mRNA breakdown, deadenylation-dependent decay
mRNA catabolic process, deadenylation-dependent
mRNA catabolic process, deadenylylation-dependent
mRNA catabolism, deadenylation-dependent
mRNA catabolism, deadenylylation-dependent
mRNA degradation, deadenylation-dependent decay
nuclear mRNA catabolic process, deadenylation-dependent decay

Definition

A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.

References

Reactome:R-HSA-429914

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

has parts: deadenylation-dependent decapping of nuclear-transcribed mRNA nuclear-transcribed mRNA poly(A) tail shortening

deadenylation-dependent decapping of nuclear-transcribed mRNA nuclear-transcribed mRNA poly(A) tail shortening Show first 5 Terms
is a type of: mRNA destabilization nuclear-transcribed mRNA catabolic process

mRNA destabilization nuclear-transcribed mRNA catabolic process Show first 5 Terms
negatively regulated by: negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay Show first 5 Terms
positively regulated by: positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay Show first 5 Terms
regulated by: regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay Show first 5 Terms

Phenotype

Phenotype caused by Genes