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Human Disease

NUT midline carcinoma

Term ID
DOID:0060463
Synonyms
  • nuclear protein in testis midline carcinoma
Definition
A carcinoma that is characterized by a BRD4-NUT translocation involving the rearrangement of the bromodomain-containing protein 4 (BRD4) and the gene encoding nuclear protein of the testis (NUT) at 15q14, BRD4-NUT t(15;19)(q14;q13.1) and arises from midline epithelial structures, most commonly the head, neck, and mediastinum. (5)
References
  • NCI:C45716
  • SNOMEDCT_US_2023_03_01:733922002
  • UMLS_CUI:C1707291
Ontology
Human Disease   ( DOID:0060463 )
Relationships
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Genes Involved
Zebrafish Models