non-classical monocyte

Term ID

CL:0000875

Synonyms

patrolling monocyte
resident monocyte

Definition

A type of monocyte characterized by low expression of CCR2, low responsiveness to monocyte chemoattractant CCL2/MCP1, low phagocytic activity, and decrease size relative to classical monocytes, but increased co-stimulatory activity. May also play a role in tissue repair. (4)

References

Ontology

Cell Ontology

Relationships

develops from: intermediate monocyte

intermediate monocyte Show first 5 Terms
is a type of: monocyte

monocyte Show first 5 Terms
has subtype: CD14-low, CD16-positive monocyte Gr1-low non-classical monocyte

CD14-low, CD16-positive monocyte Gr1-low non-classical monocyte Show first 5 Terms
bearer_of: decreased size

decreased size Show first 5 Terms
capable_of: lymphocyte costimulation

lymphocyte costimulation Show first 5 Terms
has_completed: monocyte differentiation

monocyte differentiation Show first 5 Terms
has_high_plasma_membrane_amount: CX3C chemokine receptor 1

CX3C chemokine receptor 1 Show first 5 Terms
lacks_plasma_membrane_part: C-C chemokine receptor type 2 CD3 epsilon CD19 molecule membrane-spanning 4-domains subfamily A member 1

C-C chemokine receptor type 2 CD3 epsilon CD19 molecule membrane-spanning 4-domains subfamily A member 1 Show first 5 Terms