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Cell Ontology

T-helper 1 cell

Term ID

CL:0000545

Synonyms

helper T cell type 1
T helper cells type 1
T(H)-1 cell
Th1 CD4+ T cell
Th1 cell
Th1 T cell
Th1 T lymphocyte
Th1 T-cell
Th1 T-lymphocyte

Definition

A CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive, CXCR3-positive, CCR6-negative, and is capable of producing interferon-gamma. (3)

References

BTO:0001678
FMA:84382

Ontology

Cell Ontology

Relationships

develops from: activated CD4-positive, alpha-beta T cell

activated CD4-positive, alpha-beta T cell Show first 5 Terms
is a type of: CD4-positive helper T cell

CD4-positive helper T cell Show first 5 Terms
capable_of: type II interferon production

type II interferon production Show first 5 Terms
has_part: T-box transcription factor TBX21

T-box transcription factor TBX21 Show first 5 Terms
has_plasma_membrane_part: C-X-C chemokine receptor type 3

C-X-C chemokine receptor type 3 Show first 5 Terms
lacks_plasma_membrane_part: C-C chemokine receptor type 6

C-C chemokine receptor type 6 Show first 5 Terms