Search Ontology:
ChEBI

PS-1145

Term ID
CHEBI:94801
Synonyms
  • IKK inhibitor X
  • N-(6-chloro-9H-beta-carbolin-8-yl)pyridine-3-carboxamide
  • N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)-3-pyridinecarboxamide
  • N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)nicotinamide
  • N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)pyridine-3-carboxamide
  • PS 1145
  • PS1145
Definition
A member of the class of beta-carbolines that is 9H-beta-carboline substituted by chloro and (pyridin-3-ylcarbonyl)amino groups at positions 6 and 8, respectively. It is a IkappaB kinase beta (IKKbeta) inhibitor (IC50 = 88 nM).
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from PS-1145
Phenotype where environments contain PS-1145
Phenotype modified by environments containing PS-1145
Human Disease Model
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