Search Ontology:
ChEBI
erastin
- Term ID
- CHEBI:94287
- Synonyms
-
- 2-(1-{4-[(4-chlorophenoxy)acetyl]piperazin-1-yl}ethyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one
- 2-[1-[4-[2-(4-chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone
- Definition
- A member of the class of quinazolines that is quinazolin-4(3H)-one in which the hydrogens at positions 2 and 3 are replaced by 1-{4-[(4-chlorophenoxy)acetyl]piperazin-1-yl}ethyl and 2-ethoxyphenyl groups, respectively. It is an inhibitor of voltage-dependent anion-selective channels (VDAC2 and VDAC3) and a potent ferroptosis inducer.
- References
-
- CAS:571203-78-6
- Chemspider:9390002
- KEGG:C21478
- LINCS:LSM-4914
- PMID:12676586
- PMID:17568748
- PMID:22832321
- PMID:26231156
- PMID:30522056
- PMID:31273299
- PMID:31464035
- PMID:31921655
- PMID:31974380
- PMID:31997820
- PMID:32089268
- PMID:32209255
- PMID:32606760
- PMID:32608563
- PMID:32642794
- PMID:32793311
- PMID:32893325
- PMID:32945484
- PMID:32979793
- PMID:33245979
- PMID:33333051
- PMID:33378529
- PMID:33609745
- PMID:33649848
- PMID:33675143
- PMID:33681481
- PMID:33864570
- PMID:33882617
- PMID:34012798
- Wikipedia:Erastin
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
Phenotype
Phenotype resulting from erastin
Phenotype where environments contain erastin
Phenotype modified by environments containing erastin
Human Disease / Model Data