Search Ontology:
ChEBI
SB225002
- Term ID
- CHEBI:93074
- Synonyms
-
- 1-(2-bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea
- N-(2-hydroxy-4-nitrophenyl)-N'-(2-bromophenyl)urea
- PD 157695
- PD-157695
- PD157695
- SB 225002
- SB-225002
- Definition
- A member of the class of phenylureas that is urea in which one of the amino groups is substituted by a (2-bromophenyl)amino group while the other is substituted by a (2-hydroxy-4-nitrophenyl)amino group. It is a potent CXCR2 chemokine receptor antagonist (IC50 = 22 nM).
- References
-
- CAS:182498-32-4
- LINCS:LSM-3367
- PMID:12628493
- PMID:18653784
- PMID:19264522
- PMID:20021889
- PMID:23359652
- PMID:23611835
- PMID:26302043
- PMID:29765453
- PMID:29917166
- PMID:30829852
- PMID:31494226
- PMID:31927212
- PMID:32119843
- PMID:32616311
- PMID:32639881
- PMID:32736336
- PMID:33517283
- PMID:33773907
- PMID:33785307
- PMID:34146540
- PMID:35264061
- PMID:35647855
- PMID:35856448
- PMID:36614059
- PMID:36872429
- PMID:37063917
- PMID:37481938
- PMID:37824136
- PMID:38493581
- PMID:38501672
- PMID:38704076
- Reaxys:10689013
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from SB225002
Phenotype where environments contain SB225002
Phenotype modified by environments containing SB225002
Human Disease Model