Search Ontology:
ChEBI

abexinostat

Term ID
CHEBI:92223
Synonyms
  • 3-[(dimethylamino)methyl]-N-[2-[4-(hydroxycarbamoyl)phenoxy]ethyl]-1-benzofuran-2-carboxamide
  • 3-[(dimethylamino)methyl]-N-[2-[4-[(hydroxyamino)-oxomethyl]phenoxy]ethyl]-2-benzofurancarboxamide
  • 3-[(dimethylamino)methyl]-N-[2-[4-[(hydroxyamino)carbonyl]phenoxy]ethyl]-2-benzofurancarboxamide
  • 3-[(dimethylamino)methyl]-N-{2-[4-(hydroxycarbamoyl)phenoxy]ethyl}-1-benzofuran-2-carboxamide
  • abexinostat
  • abexinostatum
  • CRA 024781
  • CRA 24781
  • CRA-024781
  • PCI 24781
  • PCI-24781
  • PZP-115891
  • PZP115891
  • S-78454
  • S78454
Definition
A 1-benzofuran substituted by {2-[4-(hydroxycarbamoyl)phenoxy]ethyl}aminocarbonyl and (dimethylamino)methyl groups at positions 2 and 3, respectively. It is a potent pan-HDAC inhibitor whose major target is HDAC1 (Ki = 7 nM).
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from abexinostat
Phenotype where environments contain abexinostat
Phenotype modified by environments containing abexinostat
Human Disease Model
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