Search Ontology:
ChEBI
HMN-214
- Term ID
- CHEBI:91440
- Synonyms
-
- (E)-4-[2-[2-(N-acetyl-N-[4-methoxybenzenesulfonyl]amino)stilbazole]]1-oxide
- (E)-4-[2-[2-[N-acetyl-N-[(p-methoxyphenyl)sulfonyl]amino]phenyl]ethenyl]pyridine 1-oxide
- HMN 214
- HMN214
- IVX 214
- IVX-214
- IVX214
- N-[(4-methoxyphenyl)sulfonyl]-N-[2-[(1E)-2-(1-oxido-4-pyridinyl)ethenyl]phenyl]acetamide
- N-[(4-methoxyphenyl)sulfonyl]-N-{2-[(E)-2-(1-oxidopyridin-4-yl)ethenyl]phenyl}acetamide
- Definition
- An N-sulfonylcarboxamide that is N-[(4-methoxyphenyl)sulfonyl]acetamide in which the hydrogen of the NH group is substituted by a 2-[(E)-2-(1-oxidopyridin-4-yl)ethenyl]phenyl group. It is a potent inhibitor of polo-like kinase 1 (PLK1) that exhibits antineoplastic activity.
- References
-
- CAS:173529-46-9
- LINCS:LSM-1192
- PMID:14583495
- PMID:14586206
- PMID:15605126
- PMID:16951237
- PMID:19474163
- PMID:25681050
- PMID:35631350
- PMID:36830618
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from HMN-214
Phenotype where environments contain HMN-214
Phenotype modified by environments containing HMN-214
Human Disease / Model Data