tenofovir alafenamide fumarate

Term ID

CHEBI:90923

Synonyms

bis{9-[(2R,5S,7E)-2,7,10-trimethyl-5,8-dioxo-5-phenoxy-3,9-dioxa-6-aza-5lambda5-phosphaundecan-1-yl]-9H-purin-6-aminium} (2E)-but-2-enedioate
bis{propan-2-yl N-[(S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl]-L-alaninate} (2E)-but-2-enedioate
GS-7340-03
TAF
tenofovir alafenamide hemifumarate
Vemlidy

Definition

A fumarate salt prepared from tenofovir alafenamide by reaction of one molecule of fumaric acid for every two molecules of tenofovir alafenamide. A prodrug for tenofovir, it is used in combination therapy for the treatment of HIV-1 infection.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: fumarate salt

fumarate salt Show first 5 Terms
has_part: tenofovir alafenamide(1+)

tenofovir alafenamide(1+) Show first 5 Terms
has_role: antiviral drug HIV-1 reverse transcriptase inhibitor prodrug

antiviral drug HIV-1 reverse transcriptase inhibitor prodrug Show first 5 Terms
inverse has_part: Descovy Genvoya Odefsey

Descovy Genvoya Odefsey Show first 5 Terms

Phenotype

Phenotype resulting from tenofovir alafenamide fumarate

Phenotype where environments contain tenofovir alafenamide fumarate

Phenotype modified by environments containing tenofovir alafenamide fumarate

Human Disease Model