Search Ontology:
ChEBI
DEL-22379
- Term ID
- CHEBI:90905
- Synonyms
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- DEL22379
- N-{(3Z)-3-[(5-methoxy-1H-indol-3-yl)methylene]-2-oxo-2,3-dihydro-1H-indol-5-yl}-3-(piperidin-1-yl)propanamide
- N-{(3Z)-3-[(5-methoxy-1H-indol-3-yl)methylene]-2-oxo-2,3-dihydro-1H-indol-5-yl}-3-(piperidin-1-yl)propionamide
- Definition
- An oxindole that is 5-amino-oxindole in which the 5-amino group has undergone formal condensation with the carboxy group of 3-(piperidin-1-yl)propanoic acid to give the corresponding carboxamide and in which the hydrogens at position 3 have been replaced by a (5-methoxy-1H-indol-3-yl)methylene group (Z configuration). It is an inhibitor of extracellular signal-regulated kinase (ERK) dimerisation.
- References
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- PMID:26267534
- Reaxys:18638308
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_role
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Phenotype
Phenotype resulting from DEL-22379
Phenotype where environments contain DEL-22379
Phenotype modified by environments containing DEL-22379
Human Disease Model