Search Ontology:
ChEBI
tipiracil
- Term ID
- CHEBI:90879
- Synonyms
-
- 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]pyrimidine-2,4(1H,3H)-dione
- tipiracil
- Definition
- A member of the class of pyrimidones that is uracil substituted by chloro and (2-iminopyrrolidin-1-yl)methyl groups at positions 5 and 6 respectively. Used (as the hydrochloride salt) in combination with trifluridine, a nucleoside metabolic inhibitor, for treatment of advanced/relapsed unresectable colorectal cancer.
- References
-
- CAS:183204-74-2
- Drug_Central:4893
- PMID:24562648
- PMID:25230742
- PMID:25750295
- PMID:25812794
- PMID:25900515
- PMID:25901475
- PMID:25970050
- PMID:26084259
- PMID:26163340
- PMID:26197742
- PMID:26254349
- PMID:26370544
- PMID:26428513
- PMID:26509228
- PMID:26535019
- PMID:26609205
- PMID:26616466
- PMID:26677869
- PMID:26722024
- PMID:26723516
- PMID:26730280
- Reaxys:9272220
- Wikipedia:Tipiracil
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_functional_parent
-
- has_role
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- inverse is_conjugate_acid_of
-
- is_conjugate_base_of
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Phenotype
Phenotype resulting from tipiracil
Phenotype where environments contain tipiracil
Phenotype modified by environments containing tipiracil
Human Disease Model