ACT-333679

Term ID

CHEBI:90848

Synonyms

ACT 333679
ACT333679
MRE 269
MRE-269
MRE269
{4-[(5,6-diphenylpyrazin-2-yl)(propan-2-yl)amino]butoxy}acetic acid

Definition

A member of the class of pyrazines that is {4-[(propan-2-yl)(pyrazin-2-yl)amino]butoxy}acetic acid carrying two additional phenyl substituents at positions 5 and 6 on the pyrazine ring. The active metabolite of selexipag, an orphan drug used for the treatment of pulmonary arterial hypertension.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic amine ether monocarboxylic acid pyrazines sulfonamide ... Show All 6 Terms

aromatic amine ether monocarboxylic acid pyrazines sulfonamide tertiary amino compound Show first 5 Terms
has_role: drug metabolite orphan drug platelet aggregation inhibitor prostacyclin receptor agonist vasodilator agent

drug metabolite orphan drug platelet aggregation inhibitor prostacyclin receptor agonist vasodilator agent Show first 5 Terms
inverse has_functional_parent: selexipag

selexipag Show first 5 Terms

Phenotype

Phenotype resulting from ACT-333679

Phenotype where environments contain ACT-333679

Phenotype modified by environments containing ACT-333679

Human Disease Model