Search Ontology:
ChEBI
pamapimod
- Term ID
- CHEBI:90685
- Synonyms
-
- 6-(2,4-difluorophenoxy)-2-[(1,5-dihydroxypentan-3-yl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one
- pamapimod
- R1503
- Ro 4402257
- Definition
- A member of the class of pyridopyrimidines that is 8-methylpyrido[2,3-d]pyrimidin-7(8H)-one carrying additional (1,5-dihydroxypentan-3-yl)amino and 2,4-difluorophenoxy substituents at positions 2 and 6 respectively. It is a potent inhibitor of MAPK and is used for treatment of rheumatoid arthritis.
- References
-
- CAS:449811-01-2
- KEGG:D08963
- PDBeChem:FLW
- PMID:18776065
- PMID:19180516
- PMID:19357113
- PMID:20100913
- PMID:20666701
- PMID:21375264
- PMID:21612741
- PMID:26279429
- Reaxys:18704012
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
Phenotype
Phenotype resulting from pamapimod
Phenotype where environments contain pamapimod
Phenotype modified by environments containing pamapimod
Human Disease / Model Data