Search Ontology:
ChEBI

sotrastaurin

Term ID
CHEBI:90531
Synonyms
  • 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]-1H-pyrrole-2,5-dione
  • AEB 071
  • AEB-071
  • AEB071
  • sotrastaurin
  • sotrastaurina
  • sotrastaurine
  • sotrastaurinum
Definition
A member of the class of maleimides that is maleimide which is substituted at position 3 by an indol-3-yl group and at position 4 by a quinazolin-4-yl group, which in turn is substituted at position 2 by a 4-methylpiperazin-1-yl group. It is a potent and selective inhibitor of protein kinase C and has been investigated as an immunosuppresant in renal transplant patients.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from sotrastaurin
Phenotype where environments contain sotrastaurin
Phenotype modified by environments containing sotrastaurin
Human Disease Model
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