TG101209

Term ID

CHEBI:90304

Synonyms

N-tert-butyl-3-[(5-methyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]benzenesulfonamide
TG 101209
TG-101209

Definition

A member of the class of pyrimidines that is 5-methylpyrimidine-2,4-diamine in which the amino group at position 2 is substituted by a p-(4-methylpiperazin-1-yl)phenyl group, while that at position 4 is substituted by a m-(tert-butylsulfamoyl)phenyl group. A Janus kinase 2 (JAK2) inhibitor.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: N-alkylpiperazine N-arylpiperazine pyrimidines secondary amino compound sulfonamide

N-alkylpiperazine N-arylpiperazine pyrimidines secondary amino compound sulfonamide Show first 5 Terms
has_role: antineoplastic agent apoptosis inducer EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor

antineoplastic agent apoptosis inducer EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from TG101209

Phenotype where environments contain TG101209

Phenotype modified by environments containing TG101209

Human Disease Model