Search Ontology:
ChEBI
selumetinib
- Term ID
- CHEBI:90227
- Synonyms
-
- 5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide
- ARRY 142886
- ARRY-142886
- ARRY142886
- AZD 6244
- AZD-6244
- AZD6244
- selumetinib
- selumetinibum
- Definition
- A member of the class of benzimidazoles that is 1-methyl-1H-benzimidazole which is substituted at positions 4, 5, and 6 by fluorine, (4-bromo-2-chlorophenyl)amino, and N-(2-hydroxyethoxy)aminocarbonyl groups, respectively. It is a MEK1 and MEK2 inhibitor.
- References
-
- CAS:606143-52-6
- KEGG:D09666
- LINCS:LSM-1056
- PDBeChem:3EW
- PMID:20407895
- PMID:20978926
- PMID:21594619
- PMID:22241789
- PMID:22343622
- PMID:22394161
- PMID:22565394
- PMID:22972589
- PMID:23372439
- PMID:23444215
- PMID:23942066
- PMID:25322874
- PMID:25342139
- PMID:25379021
- PMID:25385055
- PMID:25498501
- PMID:25637165
- PMID:25887099
- PMID:26059332
- PMID:26384399
- PMID:26446942
- Reaxys:11099648
- Wikipedia:Selumetinib
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
Phenotype
Phenotype resulting from selumetinib
Phenotype where environments contain selumetinib
Phenotype modified by environments containing selumetinib
Human Disease Model