benazeprilat

Term ID

CHEBI:88200

Synonyms

• (2S)-2-{[(3S)-1-(carboxymethyl)-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl]amino}-4-phenylbutanoic acid
• (3S)-3-(((1S)-1-carboxy-3-phenylpropyl)amino)-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid
• benazepril diacid
• benazeprilat
• benazeprilate
• benazeprilatum
• CGS 14831

Definition

A benzazepine that is 1,3,4,5-tetrahydro-2H-1-benzazepin-2-one in which the hydrogen attached to the nitrogen is replaced by a carboxy methyl group and in which the 3-pro-S hydrogen is replaced by the amino group of (2S)-2-amino-4-phenylbutanoic acid. An angiotensin-converting enzyme inhibitor, it is used as its monoester prodrug benazepril in the treatment of hypertension and heart failure.

References

• CAS:86541-78-8
• HMDB:HMDB0060582
• KEGG:D03077
• Reaxys:4214792

Ontology

ChEBI  ( EBI )