(E)-3-tosylacrylonitrile

Term ID

CHEBI:85928

Synonyms

(2E)-3-[(4-methylphenyl)sulfonyl]acrylonitrile
(3E)3-(p-toluenesulfonyl)acrylonitrile
(E)-3-(4-methylphenylsulfonyl)-2-propenenenitrile
(E)-3-(p-toluenesulfonyl)acrylonitrile
BAY-11-7082
BAY-11-7821
Bay-117082
BAY-117821
beta-(cyanovinyl)-p-tolylsulfone

Definition

A nitrile that is acrylonitrile in which the hydrogen located beta,trans to the cyano group is replaced by a tosyl group. It is an inhibitor of cytokine-induced IkappaB-alpha phosphorylation in cells.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: nitrile sulfone

nitrile sulfone Show first 5 Terms
has_role: apoptosis inducer EC 2.7.11.10 (IkappaB kinase) inhibitor EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor non-steroidal anti-inflammatory drug platelet aggregation inhibitor

apoptosis inducer EC 2.7.11.10 (IkappaB kinase) inhibitor EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor non-steroidal anti-inflammatory drug platelet aggregation inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from (E)-3-tosylacrylonitrile

Phenotype where environments contain (E)-3-tosylacrylonitrile

Phenotype modified by environments containing (E)-3-tosylacrylonitrile

Human Disease Model