probucol

Term ID

CHEBI:8427

Synonyms

• 4,4'- (Isopropylidenedithio)bis(2,6-di-tert-butylphenol)
• 4,4'-(propane-2,2-diyldisulfanediyl)bis(2,6-di-tert-butylphenol)
• Acetone bis(3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole
• Biphenabid
• Bisbid
• Bisphenabid
• DH-581
• Lesterol
• Lorelco
• Lurselle
• probucol
• probucolum
• Serterol
• Superlipid

Definition

A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.

References

• CAS:23288-49-5
• DrugBank:DB01599
• Drug_Central:2269
• HMDB:HMDB0015537
• KEGG:C07373
• KEGG:D00476
• LINCS:LSM-3617
• PMID:22305809
• PMID:23107872
• PMID:23167559
• PMID:23334712
• PMID:23363981
• PMID:23378294
• PMID:23443157
• PMID:23741215
• Patent:CN101423484
• Patent:CN101455842
• Patent:CN102973535
• Patent:FR1561853
• Patent:US3576883
• Patent:US3862332
• Reaxys:2026253
• Wikipedia:Probucol

Ontology

ChEBI  ( EBI )

Resources

CTD