penciclovir

Term ID

CHEBI:7956

Synonyms

• 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-1,9-dihydro-6H-purin-6-one
• 9-(4-hydroxy-3-(hydroxymethyl)butyl)guanine
• 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine
• 9-[2-hydroxy-1-(hydroxymethyl)-ethoxymethyl]guanine
• 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine
• PCV
• PE2
• penciclovir
• penciclovirum

Definition

A member of the class of 2-aminopurines that is guanine in which the hydrogen at position 9 is substituted by a 4-hydroxy-3-(hydroxymethyl)but-1-yl group. An antiviral drug, it is administered topically for treatment of herpes labialis. A prodrug, famciclovir, is used for oral administration.

References

• CAS:39809-25-1
• DrugBank:DB00299
• Drug_Central:2079
• HMDB:HMDB0014444
• KEGG:C07417
• KEGG:D05407
• LINCS:LSM-5587
• PDBeChem:PE2
• PMID:3040998
• Patent:US5075445
• Reaxys:4501039
• Wikipedia:Penciclovir

Ontology

ChEBI  ( EBI )