phosphorothioate oligonucleotide

Term ID

CHEBI:76674

Synonyms

oligo(nucleoside phosphorothioate)
oligo(nucleoside phosphorothioate)s
oligonucleotide phosphorothioate
oligonucleotide phosphorothioates
OPS
phosphorothioate DNA
phosphorothioate oligonucleotides
PS DNA
PS-DNA
S-oligo
S-oligos

Definition

An oligonucleotide in which one of the non-bridging oxygens in each phosphodiester linkage has been replaced by sulfur. The main application of phosphorothioate linkages in an oligonucleotide is to protect the oligonucleotide from nuclease degradation.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: oligonucleotide

oligonucleotide Show first 5 Terms
has subtype: 5'-AsGsCsCsGsCsGsAsCsTsTsCsTsAsGsAsCsT-3' 5'-CsGsGsCsTsCsCsAsTsGsTsAsCsAsGsCsAsTsGsCsG-3' 5'-GsCsAsGsTsCsTsAsTsTsAsCsTsGsTsGsCsGsAsGsA-3' 5'-GsCsCsGsAsGsGsTsCsCsAsTsGsTsCsGsTsAsCsGsC-3' 5'-GsCsGsTsAsCsGsAsCsAsTsGsGsAsCsCsTsCsGsGsC-3' ... Show All 7 Terms

5'-AsGsCsCsGsCsGsAsCsTsTsCsTsAsGsAsCsT-3' 5'-CsGsGsCsTsCsCsAsTsGsTsAsCsAsGsCsAsTsGsCsG-3' 5'-GsCsAsGsTsCsTsAsTsTsAsCsTsGsTsGsCsGsAsGsA-3' 5'-GsCsCsGsAsGsGsTsCsCsAsTsGsTsCsGsTsAsCsGsC-3' 5'-GsCsGsTsAsCsGsAsCsAsTsGsGsAsCsCsTsCsGsGsC-3' 5'-TsGsTsGsGsGsTsTsAsAsGsAsCsTsTsTsTsTsAsCsC-3' d(Gs)19dG Show first 5 Terms

Phenotype

Phenotype resulting from phosphorothioate oligonucleotide

Phenotype where environments contain phosphorothioate oligonucleotide

Phenotype modified by environments containing phosphorothioate oligonucleotide

Human Disease Model