5-(N,N-hexamethylene)amiloride

Term ID

CHEBI:76400

Synonyms

3-amino-5-(azepan-1-yl)-N-carbamimidoyl-6-chloropyrazine-2-carboxamide
3-Amino-6-chloro-5-(1-homopiperidyl)-N-(diaminomethylene)pyrazinecarboxamide
Hexamethylene amiloride
Hexamethyleneamiloride
HMA
HMA-5

Definition

A member of the class of pyrazines that is amiloride in which the two amino hydrogens at position N-5 are replaced by a hexamethylene moiety, resulting in the formation of an azepane ring.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: aromatic amine azepanes guanidines monocarboxylic acid amide organochlorine compound ... Show All 6 Terms

aromatic amine azepanes guanidines monocarboxylic acid amide organochlorine compound pyrazines Show first 5 Terms
has_functional_parent: amiloride

amiloride Show first 5 Terms
has_role: antineoplastic agent apoptosis inducer odorant receptor antagonist sodium channel blocker

antineoplastic agent apoptosis inducer odorant receptor antagonist sodium channel blocker Show first 5 Terms

Phenotype

Phenotype resulting from 5-(N,N-hexamethylene)amiloride

Phenotype where environments contain 5-(N,N-hexamethylene)amiloride

Phenotype modified by environments containing 5-(N,N-hexamethylene)amiloride

Human Disease Model