Search Ontology:
ChEBI
naproxcinod
- Term ID
- CHEBI:76254
- Synonyms
-
- (S)-2-(6-Methoxy-2-naphthyl)propanoic acid 4-nitrooxybutyl ester
- 4-(nitrooxy)butyl (2S)-2-(6-methoxy-2-naphthyl)propanoate
- AZD 3582
- AZD3582
- HCT 3012
- naproxcinod
- naproxcinodum
- Naproxen-N-butyl nitrate
- Nitronaproxen
- Definition
- A carboxylic ester obtained by formal condensation of the carboxy group of naproxen with the hydroxy group of 4-(nitrooxy)butanol. A cyclooxygenase-inhibiting nitric oxide donator that is metabolised to naproxen and a nitric oxide donating moiety, effective in treatment of osteoarthritis.
- References
-
- CAS:163133-43-5
- Drug_Central:4674
- KEGG:D09568
- PMID:16784252
- PMID:17596112
- PMID:19392579
- PMID:19393822
- PMID:19411388
- PMID:19446261
- PMID:19557204
- PMID:19733721
- PMID:19798455
- PMID:20202489
- PMID:20677266
- PMID:20722026
- PMID:20828790
- PMID:21272053
- PMID:21275896
- PMID:21371681
- PMID:21439116
- PMID:21542252
- PMID:21545399
- PMID:21756233
- PMID:22425883
- PMID:22852285
- PMID:22870450
- PMID:23060406
- Patent:US2008269323
- Patent:WO2009000723
- Patent:WO2012152438
- Reaxys:8432594
- Wikipedia:Naproxcinod
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_functional_parent
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- has_role
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Phenotype
Phenotype resulting from naproxcinod
Phenotype where environments contain naproxcinod
Phenotype modified by environments containing naproxcinod
Human Disease Model