loxoprofen

Term ID

CHEBI:76172

Synonyms

(+-)-((2-oxocyclopentyl)methyl)hydratropic acid
2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid
loxoprofen
loxoprofene
loxoprofeno
loxoprofenum

Definition

A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-[(2-oxocyclopentyl)methyl]phenyl group. A prodrug that is rapidly converted into its active trans-alcohol metabolite following oral administration.

References

CAS:68767-14-6
Drug_Central:1615
HMDB:HMDB0041920
KEGG:D08149
LINCS:LSM-5054
Patent:EP1767218
Patent:WO2008020270
Reaxys:2860055
Wikipedia:Loxoprofen

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: cyclopentanones monocarboxylic acid

cyclopentanones monocarboxylic acid Show first 5 Terms
has_functional_parent: propionic acid

propionic acid Show first 5 Terms
has_role: antipyretic EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor non-narcotic analgesic non-steroidal anti-inflammatory drug prodrug

antipyretic EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor non-narcotic analgesic non-steroidal anti-inflammatory drug prodrug Show first 5 Terms
inverse has_functional_parent: (2S)-2-(4-{[(1R,2S)-2-hydroxycyclopentyl]methyl}phenyl)propanoic acid

(2S)-2-(4-{[(1R,2S)-2-hydroxycyclopentyl]methyl}phenyl)propanoic acid Show first 5 Terms
inverse is_conjugate_base_of: loxoprofen(1-)

loxoprofen(1-) Show first 5 Terms
is_conjugate_acid_of: loxoprofen(1-)

loxoprofen(1-) Show first 5 Terms

Phenotype

Phenotype resulting from loxoprofen

Phenotype where environments contain loxoprofen

Phenotype modified by environments containing loxoprofen

Human Disease Model