(R,R)-tramadol hydrochloride

Term ID

CHEBI:75733

Synonyms

(+)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride
(+)-tramadol hydrochloride
(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride
[(1R,2R)-2-hydroxy-2-(3-methoxyphenyl)cyclohexyl]-N,N-dimethylmethanaminium chloride

Definition

A hydrochloride resulting from the reaction of (R,R)-tramadol with 1 molar equivalent of hydrogen chloride; the (R,R)-enantiomer of the racemic opioid analgesic tramadol hydrochloride, it exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer.

References

CAS:53611-16-8
Reaxys:6164343

Ontology

ChEBI ( EBI )

Relationships

is a type of: hydrochloride

hydrochloride Show first 5 Terms
has_part: (R,R)-tramadol(1+)

(R,R)-tramadol(1+) Show first 5 Terms
has_role: adrenergic uptake inhibitor antitussive capsaicin receptor antagonist delta-opioid receptor agonist kappa-opioid receptor agonist ... Show All 12 Terms

adrenergic uptake inhibitor antitussive capsaicin receptor antagonist delta-opioid receptor agonist kappa-opioid receptor agonist mu-opioid receptor agonist muscarinic antagonist nicotinic antagonist NMDA receptor antagonist opioid analgesic serotonergic antagonist serotonin uptake inhibitor Show first 5 Terms
inverse has_part: tramadol hydrochloride

tramadol hydrochloride Show first 5 Terms
inverse is_enantiomer_of: (S,S)-tramadol hydrochloride

(S,S)-tramadol hydrochloride Show first 5 Terms
is_enantiomer_of: (S,S)-tramadol hydrochloride

(S,S)-tramadol hydrochloride Show first 5 Terms

Phenotype

Phenotype resulting from (R,R)-tramadol hydrochloride

Phenotype where environments contain (R,R)-tramadol hydrochloride

Phenotype modified by environments containing (R,R)-tramadol hydrochloride

Human Disease Model