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ChEBI

5-(2,2-diferuloylethen-1-yl)thalidomide

Term ID
CHEBI:74775
Synonyms
  • 2-(2,6-dioxopiperidin-3-yl)-5-{(4E)-5-(4-hydroxy-3-methoxyphenyl)-2-[(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl]-3-oxopenta-1,4-dien-1-yl}-1H-isoindole-1,3(2H)-dione
  • 5-{(4E)-5-(4-hydroxy-3-methoxyphenyl)-2-[(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl]-3-oxopenta-1,4-dien-1-yl}thalidomide
  • 5-{2,2-di[(1E)-1-(4-hydroxy-3-methoxyphenyl)-3-oxoprop-1-en-3-yl]ethenyl}thalidomide
Definition
A dicarboximide that is thalidomide substituted at position 5 by an ethenyl group, which in turn is substituted by two feruloyl groups at position 2. The compound is a hybrid based on the structures of thalidomide and curcumin and has been found to exhibit cytotoxicity against human multiple myeloma cells.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_functional_parent
has_role
Phenotype
Phenotype resulting from 5-(2,2-diferuloylethen-1-yl)thalidomide
Phenotype where environments contain 5-(2,2-diferuloylethen-1-yl)thalidomide
Phenotype modified by environments containing 5-(2,2-diferuloylethen-1-yl)thalidomide
Human Disease Model