Search Ontology:
ChEBI
lomitapide
- Term ID
- CHEBI:72297
- Synonyms
-
- AEGR 733
- AEGR 773
- AEGR-773
- AEGR733
- AEGR773
- BMS 201038
- BMS201038
- Lojuxta
- lomitapida
- lomitapide
- lomitapidum
- N-(2,2,2-trifluoroethyl)-9-{4-[4-({[4'-(trifluoromethyl)biphenyl-2-yl]carbonyl}amino)piperidin-1-yl]butyl}-9H-fluorene-9-carboxamide
- Definition
- A member of the class of benzamides obtained by formal condensation of the carboxy group of 4'-(trifluoromethyl)biphenyl-2-carboxylic acid with the primary amino group of 9-[4-(4-aminopiperidin-1-yl)butyl]-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide. Used (as its mesylate salt) as a complement to a low-fat diet and other lipid-lowering treatments in patients with homozygous familial hypercholesterolemia.
- References
-
- CAS:182431-12-5
- DrugBank:DB08827
- Drug_Central:4721
- KEGG:D09637
- PMID:17215532
- PMID:20127562
- PMID:21846156
- PMID:22963620
- PMID:23122767
- PMID:23122768
- PMID:23147576
- PMID:24366202
- PMID:25257075
- PMID:25702706
- PMID:26120010
- PMID:26686567
- PMID:27055957
- PMID:27232459
- PMID:27785928
- PMID:28154305
- PMID:28239069
- PMID:28255870
- PMID:28432645
- PMID:28598687
- PMID:28716835
- Patent:US2003162788
- Patent:US2008161279
- Patent:US2010273829
- Patent:US2011288064
- Patent:US2011288110
- Patent:US2012035204
- Patent:US2012071458
- Reaxys:13754976
- Wikipedia:Lomitapide
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
- inverse is_conjugate_acid_of
-
- is_conjugate_base_of
-
Show first 5 Terms
Phenotype
Phenotype resulting from lomitapide
Phenotype where environments contain lomitapide
Phenotype modified by environments containing lomitapide
Human Disease / Model Data