Search Ontology:
ChEBI
BKM120
- Term ID
- CHEBI:71954
- Synonyms
-
- 5-[2,6-di(morpholin-4-yl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine
- BKM 120
- NVP-BKM120
- Definition
- An aminopyridine that is 4-(trifluoromethyl)pyridin-2-amine substituted at position 5 by a 2,6-di(morpholin-4-yl)pyrimidin-4-y group. A selective PI3K inhibitor with anti-tumour properties.
- References
-
- CAS:1202777-78-3
- LINCS:LSM-1148
- PMID:21169255
- PMID:21362200
- PMID:22037215
- PMID:22049316
- PMID:22065080
- PMID:22159814
- PMID:22162589
- PMID:22188813
- PMID:22207485
- PMID:22355357
- PMID:22543857
- PMID:22619567
- PMID:22653967
- PMID:22682985
- PMID:22737248
- PMID:22781393
- PMID:22915751
- PMID:22915752
- PMID:23238639
- PMID:23300274
- PMID:23319457
- Patent:WO2007084786
- Patent:WO2012044727
- Patent:WO2012109423
- Reaxys:12938097
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from BKM120
Phenotype where environments contain BKM120
Phenotype modified by environments containing BKM120
Human Disease Model