Search Ontology:
ChEBI
dactolisib
- Term ID
- CHEBI:71952
- Synonyms
-
- 2-methyl-2-{4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl]phenyl}propanenitrile
- BEZ 235
- BEZ-235
- BEZ235
- NVP BEZ235
- NVP-BEZ 235
- NVP-BEZ235
- NVPBEZ235
- Definition
- An imidazoquinoline that is 3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinoline substituted at position 1 by a 4-(1-cyanoisopropyl)phenyl group and at position 8 by a quinolin-3-yl group. A dual PI3K/mTOR inhibitor used in cancer treatment.
- References
-
- CAS:915019-65-7
- LINCS:LSM-4255
- PMID:22020918
- PMID:22154651
- PMID:22218692
- PMID:22287733
- PMID:22299028
- PMID:22355272
- PMID:22401294
- PMID:22415236
- PMID:22452803
- PMID:22560334
- PMID:22662154
- PMID:22727754
- PMID:22858987
- PMID:22895065
- PMID:22920938
- PMID:22960230
- PMID:22989521
- PMID:23077520
- PMID:23215722
- PMID:23232026
- PMID:23300274
- PMID:23319394
- PMID:23319457
- PMID:23321494
- PMID:23343422
- Patent:WO2006122806
- Patent:WO2008064093
- Reaxys:12748665
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from dactolisib
Phenotype where environments contain dactolisib
Phenotype modified by environments containing dactolisib
Human Disease Model